DIAGNOSIS OF CHRONIC AUTOIMMUNE URTICARIA

Molotilov Boris Alexandrovich, Doctor of medical sciences, professor, head of sub-department of allergology and immunology, Penza Institute of Advanced Medical Studies, borismolotilov@yandex.ru
Orlova Ekaterina Alexandrovna, Candidate of medical sciences, assistant, sub-department of allergology and immunology, Penza Institute of Advanced Medical Studies, borismolotilov@yandex.ru
Bolts Elena Alexandrovna, Postgraduate student, Penza Institute of Advanced Medical Studies, borismolotilov@yandex.ru

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The research shows that 30-50% of patients with recurrent urticaria have an autoimmune etiology. Diagnosing patients with autoimmune urticaria is very im-portant as they need high doses of antihistamines and systemic corticosteroids during acute exacerbations. The autologous serum skin test has been conducted among 30 patients with chronic urticaria. As a result, our study revealed that 77 % of patients with chronic urticaria have positive test results, which may indicate an autoimmune mechanism of this disease. According to our data, the most reliable autoserum sample size for diagnosis of autoimmune urticaria and further treatment strategy should be 7 mm or more. In control groups the autoserum test results have all been negative, except for one case (2.5 mm).

autoimmune urticaria, diagnosis, autologus serum skin test.